The manual on “<link https: echa.europa.eu documents manual_regis_and_ppord_en.pdf _blank>How to prepare registration and PPORD dossiers” has been updated, among others things, with a new chapter on how to create a full opt-out member dossier after a dispute. The update also includes clarifications on the requirements for submitting a chemical safety report (CSR) and on how to describe intermediates uses.